| Gene Information | |
|---|---|
| Gene Name | NMU |
| Organism | Homo sapiens (Human) |
| Gene Length | 174 |
| Protein Names | Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36 (NURP36); Neuromedin precursor-related peptide 33 (NURP33); Neuromedin-U-25 (NmU-25)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000109255 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P48645 |
| Gene Card | NMU |
| Uniprot ID | P48645 |
| Pfam | PF02070 |
| In ASD | no |
| Allosteric Prediction | yes (0.073205487) |
| Ortholog in Animals | Alpaca_ NMU ( ortholog_one2one ) GuineaPig_ NMU ( ortholog_one2one ) Macaque_ NMU ( ortholog_one2one ) Mouse_ Nmu ( ortholog_one2one ) Pig_ NMU ( ortholog_one2one ) Rat_ Nmu ( ortholog_one2one ) Rabbit_ NMU ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | esophagus, skin, brain, esophagus.mucosa |
| Tissue Specificity | Expressed throughout the enteric nervous system with highest levels being found in the jejunum. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7W53 (EM 3.20A ) 7W55 (EM 2.80A ) |
| DBSNP | rs35892915 rs12108463 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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