| Gene Information | |
|---|---|
| Gene Name | NMI |
| Organism | Homo sapiens (Human) |
| Gene Length | 307 |
| Protein Names | N-myc-interactor (Nmi) (N-myc and STAT interactor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000123609 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q13287 |
| Gene Card | NMI |
| Uniprot ID | Q13287 |
| Pfam | PF07334; PF07292 |
| In ASD | no |
| Allosteric Prediction | no (-0.539398504) |
| Ortholog in Animals | Alpaca_ NMI ( ortholog_one2one ) Dog_ NMI ( ortholog_one2one ) GuineaPig_ NMI ( ortholog_one2one ) Macaque_ NMI ( ortholog_one2one ) Mouse_ Nmi ( ortholog_one2one ) Pig_ NMI ( ortholog_one2one ) Rat_ Nmi ( ortholog_one2one ) Rabbit_ NMI ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RBM43, IFI35 |
| Tissue | NA |
| Tissue Specificity | Expressed in adult spleen, liver, and kidney (PubMed:9781816). Expressed in fetal thymus, liver, placenta, spleen, lung, and kidney but not brain (PubMed:9781816). Expressed in macrophages (PubMed:29038465). {ECO:0000269|PubMed:29038465, ECO:0000269|PubMed:9781816}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1048135 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10779520, ECO:0000269|PubMed:10950963, ECO:0000269|PubMed:29377960, ECO:0000269|PubMed:9781816}. Nucleus {ECO:0000269|PubMed:10950963, ECO:0000269|PubMed:9781816}. Secreted {ECO:0000269|PubMed:29038465}. Note=Cytoplasmic NMI localizes in punctate granular structures (PubMed:9781816, PubMed:10950963). Nuclear localization increased following IFN-alpha treatment (PubMed:9781816, PubMed:10950963). Extracelullar following secretion by macrophage (PubMed:29038465). {ECO:0000269|PubMed:10950963, ECO:0000269|PubMed:29038465, ECO:0000269|PubMed:9781816}. |
| Mouse PG classification | NA |
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