Gene Information
Gene NameNME9
OrganismHomo sapiens (Human)
Gene Length330
Protein NamesThioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2)
Target NameNA
Target TypeNA
Gene Age244 ( ENSG00000181322 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ86XW9
Gene CardNME9
Uniprot IDQ86XW9
PfamPF00334; PF00085
In ASDno
Allosteric Predictionno (-0.355701467)
Ortholog in AnimalsAlpaca_ NME9 ( ortholog_one2one )
Dog_ NME9 ( ortholog_one2one )
GuineaPig_ NME9 ( ortholog_one2one )
Macaque_ NME9 ( ortholog_one2one )
Mouse_ Nme9 ( ortholog_one2one )
Pig_ NME9 ( ortholog_one2one )
Rat_ AABR07071287.1 ( ortholog_one2one )
Rabbit_ NME9 ( ortholog_one2one )
OhnologsNA
ParalogsNME8, NME2, NME7, NME1, NME4, NME6, NME3, NME5
TissueNA
Tissue SpecificityDetected at very low levels in testis, lung and brain. {ECO:0000269|PubMed:12569107}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A0A1L1SUL6}. Dynein axonemal particle {ECO:0000250|UniProtKB:Q6IRC5}. Note=Associated with microtubules. Detected in cilia of lung epithelium, and associated with the spermatid tail and manchette. {ECO:0000250|UniProtKB:A0A1L1SUL6}.
Mouse PG classificationNA
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