| Gene Information | |
|---|---|
| Gene Name | CENPB |
| Organism | Homo sapiens (Human) |
| Gene Length | 599 |
| Protein Names | Major centromere autoantigen B (Centromere protein B) (CENP-B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000125817 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P07199 |
| Gene Card | CENPB |
| Uniprot ID | P07199 |
| Pfam | PF09026; PF04218; PF03184; PF03221 |
| In ASD | no |
| Allosteric Prediction | no (-0.54040479) |
| Ortholog in Animals | Alpaca_ CENPB ( ortholog_one2one ) Dog_ CENPB ( ortholog_one2one ) GuineaPig_ CENPB ( ortholog_one2one ) Macaque_ CENPB ( ortholog_one2one ) Mouse_ Cenpb ( ortholog_one2one ) Pig_ CENPB ( ortholog_one2one ) Rat_ Cenpb ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TIGD6, POGZ, TIGD7, TIGD4, TIGD2, TIGD3, TIGD1, POGK, JRKL, TIGD5, JRK |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BW6 (NMR - ) 1HLV (X-ray 2.50A ) 1UFI (X-ray 1.65A ) 6KDR (X-ray 2.11A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00320, ECO:0000255|PROSITE-ProRule:PRU00583, ECO:0000269|PubMed:18072184}. Chromosome, centromere {ECO:0000269|PubMed:18072184}. |
| Mouse PG classification | NA |
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