| Gene Information | |
|---|---|
| Gene Name | NMDAR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 938 |
| Protein Names | Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q05586 |
| Gene Card | GRIN1 |
| Uniprot ID | Q05586 |
| Pfam | PF01094; PF10562; PF00060; PF10613 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.175933(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HQW (X-ray 1.90A ) 2NR1 (NMR - ) 3BYA (X-ray 1.85A ) 5H8F (X-ray 1.81A ) 5H8H (X-ray 2.23A ) 5H8N (X-ray 2.50A ) 5H8Q (X-ray 1.90A ) 5I2K (X-ray 2.86A ) 5I2N (X-ray 2.12A ) 5KCJ (X-ray 2.09A ) 5KDT (X-ray 2.44A ) 5TP9 (X-ray 2.40A ) 5TPA (X-ray 2.48A ) 6IRA (EM 4.50A ) 6IRF (EM 5.10A ) 6IRG (EM 5.50A ) 6IRH (EM 7.80A ) 7EOQ (EM 4.10A ) 7EOR (EM 4.00A ) 7EOS (EM 3.90A ) 7EOT (EM 3.80A ) 7EOU (EM 4.30A ) 7EU7 (EM 3.50A ) 7EU8 (EM 4.07A ) |
| DBSNP | rs200777850 rs869312865 rs148008303 rs763133592 rs3181457 rs1554770054 rs878853143 rs1833614590 rs797045047 rs1060500046 rs1833621434 rs771610568 rs387906635 rs1126448 rs797044925 rs1554770624 rs1451230055 rs1554770667 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26875626, ECO:0000269|PubMed:26919761, ECO:0000269|PubMed:28105280, ECO:0000269|PubMed:28126851, ECO:0000269|PubMed:7685113}; Multi-pass membrane protein {ECO:0000250}. Postsynaptic cell membrane {ECO:0000250}. Postsynaptic density {ECO:0000250}. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. {ECO:0000250}. |
| Mouse PG classification | NA |
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