| Gene Information | |
|---|---|
| Gene Name | NLS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 543 |
| Protein Names | Sodium-dependent lysophosphatidylcholine symporter 1 (NLS1) (Sodium-dependent LPC symporter 1) (Major facilitator superfamily domain-containing protein 2A) (HsMFSD2A) (MFSD2a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8NA29 |
| Gene Card | MFSD2A |
| Uniprot ID | Q8NA29 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | In placenta, associated with trophoblast cells. {ECO:0000269|PubMed:18988732}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7OIX (EM 3.60A ) |
| DBSNP | rs1570238098 rs1057517688 rs1057517689 rs756467073 rs776741331 rs1057519087 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26005868, ECO:0000269|PubMed:32572202}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9DA75}; Multi-pass membrane protein {ECO:0000255}. Note=Cytoplasmic punctae that may represent vesicles shuttling between the endoplasmic reticulum and the plasma membrane (PubMed:21677192). {ECO:0000269|PubMed:21677192}. |
| Mouse PG classification | NA |
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