| Gene Information | |
|---|---|
| Gene Name | NLRP7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 980 |
| Protein Names | NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000167634 ) 3 ( ENSG00000274174 ) 3 ( ENSG00000274571 ) 3 ( ENSG00000275483 ) 3 ( ENSG00000276804 ) 3 ( ENSG00000277071 ) 3 ( ENSG00000277179 ) 3 ( ENSG00000277776 ) 3 ( ENSG00000277786 ) 3 ( ENSG00000278173 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8WX94 |
| Gene Card | NLRP7 |
| Uniprot ID | Q8WX94 |
| Pfam | PF05729; PF17776; PF17779; PF02758 |
| In ASD | no |
| Allosteric Prediction | no (-1.046931623) |
| Ortholog in Animals | Alpaca_ NLRP7 ( ortholog_one2many ) Macaque_ NLRP7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NLRP9, NLRC5, NLRP14, NLRP4, CIITA, NOD1, NLRP8, NLRP10, NLRP3, NLRP5, NLRP6, NLRP11, NLRP2, PYDC2, NLRC3, NLRX1, NLRP12, NLRP13, NLRP1, NOD2 |
| Tissue | NA |
| Tissue Specificity | Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle. {ECO:0000269|PubMed:15817483, ECO:0000269|PubMed:16462743}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KM6 (NMR - ) |
| DBSNP | rs77812009 rs79513034 rs775882 rs10418277 rs104895548 rs61747414 rs775881 rs61743949 rs104895549 rs104895502 rs104895502 rs104895506 rs104895550 rs104895526 rs104895525 rs104895552 rs104895503 rs7256020 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
| click here to return to the previous page | |