| Gene Information | |
|---|---|
| Gene Name | NLRP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 994 |
| Protein Names | NACHT, LRR and PYD domains-containing protein 4 (Cancer/testis antigen 58) (CT58) (PAAD and NACHT-containing protein 2) (PAN2) (PYRIN and NACHT-containing protein 2) (PYRIN-containing APAF1-like protein 4) (PYPAF4) (Ribonuclease inhibitor 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000160505 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q96MN2 |
| Gene Card | NLRP4 |
| Uniprot ID | Q96MN2 |
| Pfam | PF13516; PF05729; PF17776; PF17779; PF02758 |
| In ASD | no |
| Allosteric Prediction | no (-0.729311528) |
| Ortholog in Animals | Alpaca_ NLRP4 ( ortholog_one2one ) Macaque_ NLRP4 ( ortholog_one2one ) Mouse_ Nlrp4c ( ortholog_one2many ) Mouse_ Nlrp4e ( ortholog_one2many ) Mouse_ Nlrp4a ( ortholog_one2many ) Mouse_ Nlrp4f ( ortholog_one2many ) Mouse_ Nlrp4b ( ortholog_one2many ) Pig_ NLRP4 ( ortholog_one2one ) Rat_ RGD1560291 ( ortholog_one2many ) Rat_ Nlrp4b ( ortholog_one2many ) Rat_ Nlrp4 ( ortholog_one2many ) Rat_ Nlrp4a ( ortholog_one2many ) |
| Ohnologs | RNH1 |
| Paralogs | NLRP9, NLRC5, NLRP14, NLRP7, CIITA, NOD1, NLRP8, NLRP10, NLRP3, NLRP5, NLRP6, NLRP11, NLRP2, PYDC2, NLRC3, NLRX1, NLRP12, NLRP13, NLRP1, NOD2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4EWI (X-ray 2.28A ) |
| DBSNP | rs441827 rs17857373 rs17857374 rs12462372 rs17854614 rs302453 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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