| Gene Information | |
|---|---|
| Gene Name | NLN |
| Organism | Homo sapiens (Human) |
| Gene Length | 704 |
| Protein Names | Neurolysin, mitochondrial (EC 3.4.24.16) (Angiotensin-binding protein) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000123213 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BYT8 |
| Gene Card | NLN |
| Uniprot ID | Q9BYT8 |
| Pfam | PF01432 |
| In ASD | no |
| Allosteric Prediction | yes (0.095317997) |
| Ortholog in Animals | Alpaca_ NLN ( ortholog_one2one ) Dog_ NLN ( ortholog_one2one ) GuineaPig_ NLN ( ortholog_one2one ) Macaque_ NLN ( ortholog_one2one ) Mouse_ Nln ( ortholog_one2one ) Pig_ NLN ( ortholog_one2one ) Rat_ Nln ( ortholog_one2one ) Rabbit_ NLN ( ortholog_one2one ) |
| Ohnologs | THOP1 |
| Paralogs | THOP1, MIPEP |
| Tissue | globus.pallidus, substantia.nigra, thalamus |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5LUZ (X-ray 2.70A ) 5LV0 (X-ray 2.70A ) |
| DBSNP | rs34339013 rs34063558 rs6863012 rs2289884 rs6860508 |
| Subcellular location [CC] | Mitochondrion intermembrane space {ECO:0000250|UniProtKB:P42676}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P42676}. |
| Mouse PG classification | NA |
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