| Gene Information | |
|---|---|
| Gene Name | LRRC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 524 |
| Protein Names | Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000137269 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BTT6 |
| Gene Card | LRRC1 |
| Uniprot ID | Q9BTT6 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-1.55353707) |
| Ortholog in Animals | Alpaca_ LRRC1 ( ortholog_one2one ) Dog_ LRRC1 ( ortholog_one2one ) GuineaPig_ LRRC1 ( ortholog_one2one ) Macaque_ LRRC1 ( ortholog_one2one ) Mouse_ Lrrc1 ( ortholog_one2one ) Pig_ LRRC1 ( ortholog_one2one ) Rat_ Lrrc1 ( ortholog_one2one ) Rabbit_ LRRC1 ( ortholog_one2one ) |
| Ohnologs | SCRIB, ERBIN |
| Paralogs | LRRC8B, LRRIQ4, LRRC18, LRCH4, LRRK1, LRRC58, LRRD1, PHLPP1, ERBIN, LRRC8C, LRCH2, MFHAS1, LRRC2, PIDD1, LRRC30, LRRC27, LRRC8E, LRRC7, LRCH1, LRRC8A, LRRC8D, LRRC10, LRRC10B, LRRC40, SHOC2, PHLPP2, LRCH3, LRRC69, LRRC39, LRRC28, SCRIB |
| Tissue | NA |
| Tissue Specificity | Expressed strongly in testis and placenta, followed by heart, lung, kidney, thyroid, trachea, colon, prostate and pancreas. {ECO:0000269|PubMed:11440998}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9349688 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11440998}. Membrane {ECO:0000269|PubMed:11440998}; Peripheral membrane protein {ECO:0000269|PubMed:11440998}. Note=Localized at the basolateral side of epithelial cells. |
| Mouse PG classification | NA |
| click here to return to the previous page | |