| Gene Information | |
|---|---|
| Gene Name | NKX3-1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 234 |
| Protein Names | Homeobox protein Nkx-3.1 (Homeobox protein NK-3 homolog A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000167034 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q99801 |
| Gene Card | NKX3-1 |
| Uniprot ID | Q99801 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | yes (0.006214076) |
| Ortholog in Animals | Alpaca_ NKX3-1 ( ortholog_one2one ) Dog_ NKX3-1 ( ortholog_one2one ) GuineaPig_ NKX3-1 ( ortholog_one2one ) Macaque_ NKX3-1 ( ortholog_one2one ) Mouse_ Nkx3-1 ( ortholog_one2one ) Pig_ NKX3-1 ( ortholog_one2one ) Rat_ Nkx3-1 ( ortholog_one2one ) Rabbit_ NKX3-1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NKX6-3, NKX2-8, NKX1-2, NKX2-1, NKX2-3, NKX2-2, NKX6-1, NKX3-2, NKX1-1, NKX2-5, NKX6-2, NKX2-6, NKX2-4 |
| Tissue | prostate, testis |
| Tissue Specificity | Highly expressed in the prostate and, at a lower level, in the testis. {ECO:0000269|PubMed:9226374, ECO:0000269|PubMed:9537602}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2L9R (NMR - ) |
| DBSNP | rs2228013 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:11137288}. |
| Mouse PG classification | NA |
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