| Gene Information | |
|---|---|
| Gene Name | SRL |
| Organism | Homo sapiens (Human) |
| Gene Length | 473 |
| Protein Names | Sarcalumenin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000185739 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86TD4 |
| Gene Card | SRL |
| Uniprot ID | Q86TD4 |
| Pfam | PF00350; PF16880 |
| In ASD | no |
| Allosteric Prediction | no (-0.54759914) |
| Ortholog in Animals | Alpaca_ SRL ( ortholog_one2one ) GuineaPig_ SRL ( ortholog_one2one ) Macaque_ SRL ( ortholog_one2one ) Mouse_ Srl ( ortholog_one2one ) Pig_ SRL ( ortholog_one2one ) Rat_ Srl ( ortholog_one2one ) Rabbit_ SRL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EPS15L1, REPS2, ITSN2, EPS15, ITSN1, EHD2, EHD4, EHD3, REPS1, EHD1 |
| Tissue | heart, skeletal.muscle, artery, left.atrium, left.ventricle, mitral.valve, penis, pulmonary.valve, tongue, atrium |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:P13666}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:P13666}; Peripheral membrane protein {ECO:0000250|UniProtKB:P13666}. Note=May associate with the sarcoplasmic reticulum membrane, via a calcium-dependent mechanism. {ECO:0000250|UniProtKB:P13666}. |
| Mouse PG classification | NA |
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