| Gene Information | |
|---|---|
| Gene Name | NKHC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1032 |
| Protein Names | Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q12840 |
| Gene Card | KIF5A |
| Uniprot ID | Q12840 |
| Pfam | PF00225 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Distributed throughout the CNS but is highly enriched in subsets of neurons. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.127407(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4UXT (EM 7.40A ) 4UXY (EM 6.50A ) 4UY0 (EM 7.70A ) |
| DBSNP | rs387907287 rs387907285 rs121434441 rs121434443 rs121434442 rs387907288 rs121434444 rs1399145820 rs1373971092 rs754373609 rs113247976 rs1555179087 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q6QLM7}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q6QLM7}. Perikaryon {ECO:0000250|UniProtKB:Q6QLM7}. Note=Concentrated in the cell body of the neurons, particularly in the perinuclear region. {ECO:0000250|UniProtKB:Q6QLM7}. |
| Mouse PG classification | NA |
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