Gene Information
Gene NameNKD2
OrganismHomo sapiens (Human)
Gene Length451
Protein NamesProtein naked cuticle homolog 2 (Naked-2) (hNkd2)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000145506 )
3 ( ENSG00000276920 )
Evolutionary StageEumetazoa
AlphaFoldDBQ969F2
Gene CardNKD2
Uniprot IDQ969F2
PfamNA
In ASDno
Allosteric Predictionno (-0.719205455)
Ortholog in AnimalsAlpaca_ NKD2 ( ortholog_one2one )
Dog_ NKD2 ( ortholog_one2one )
GuineaPig_ NKD2 ( ortholog_one2one )
Macaque_ NKD2 ( ortholog_one2one )
Mouse_ Nkd2 ( ortholog_one2one )
Pig_ NKD2 ( ortholog_one2one )
Rat_ Nkd2 ( ortholog_one2one )
OhnologsNKD1
ParalogsNKD1
Tissuelung, tricuspid.valve
Tissue SpecificityExpressed in kidney, lung, pancreas and spleen. {ECO:0000269|PubMed:11604995}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs35679233 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:15064403, ECO:0000269|PubMed:17553928}. Cytoplasm {ECO:0000269|PubMed:15064403, ECO:0000269|PubMed:17553928}. Cytoplasmic vesicle {ECO:0000269|PubMed:15064403, ECO:0000269|PubMed:17553928}.
Mouse PG classificationNA
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