| Gene Information | |
|---|---|
| Gene Name | NK1R |
| Organism | Homo sapiens (Human) |
| Gene Length | 407 |
| Protein Names | Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P25103 |
| Gene Card | TACR1 |
| Uniprot ID | P25103 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001823(Rat);0.016667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KS9 (NMR - ) 2KSA (NMR - ) 2KSB (NMR - ) 6E59 (X-ray 3.40A ) 6HLL (X-ray 3.27A ) 6HLO (X-ray 2.40A ) 6HLP (X-ray 2.20A ) 7P00 (EM 2.71A ) 7P02 (EM 2.87A ) 7RMG (EM 3.00A ) 7RMH (EM 3.10A ) 7RMI (EM 3.20A ) |
| DBSNP | rs200685841 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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