| Gene Information | |
|---|---|
| Gene Name | NIT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 276 |
| Protein Names | Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000114021 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9NQR4 |
| Gene Card | NIT2 |
| Uniprot ID | Q9NQR4 |
| Pfam | PF00795 |
| In ASD | no |
| Allosteric Prediction | no (-0.018191649) |
| Ortholog in Animals | Alpaca_ NIT2 ( ortholog_one2one ) Dog_ NIT2 ( ortholog_one2one ) GuineaPig_ NIT2 ( ortholog_one2one ) Macaque_ NIT2 ( ortholog_one2one ) Mouse_ Nit2 ( ortholog_one2one ) Pig_ NIT2 ( ortholog_one2one ) Rat_ Nit2 ( ortholog_one2one ) Rabbit_ NIT2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UPB1, NIT1 |
| Tissue | NA |
| Tissue Specificity | Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon. {ECO:0000269|PubMed:14528910, ECO:0000269|PubMed:17488281}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17851799 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17488281}. |
| Mouse PG classification | NA |
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