| Gene Information | |
|---|---|
| Gene Name | NIT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.128) (Nitrilase homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000158793 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q86X76 |
| Gene Card | NIT1 |
| Uniprot ID | Q86X76 |
| Pfam | PF00795 |
| In ASD | no |
| Allosteric Prediction | no (-0.373279345) |
| Ortholog in Animals | Alpaca_ NIT1 ( ortholog_one2one ) Dog_ NIT1 ( ortholog_one2one ) GuineaPig_ NIT1 ( ortholog_one2one ) Macaque_ NIT1 ( ortholog_one2one ) Mouse_ Nit1 ( ortholog_one2one ) Pig_ NIT1 ( ortholog_one2one ) Rat_ Nit1 ( ortholog_one2one ) Rabbit_ NIT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NIT2, UPB1 |
| Tissue | NA |
| Tissue Specificity | Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9671749}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001790(Rat);0.083738(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 2]: Mitochondrion {ECO:0000250|UniProtKB:Q8VDK1}.; [Isoform 1]: Cytoplasm {ECO:0000250|UniProtKB:Q8VDK1}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |