| Gene Information | |
|---|---|
| Gene Name | NIRF |
| Organism | Homo sapiens (Human) |
| Gene Length | 802 |
| Protein Names | E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96PU4 |
| Gene Card | UHRF2 |
| Uniprot ID | Q96PU4 |
| Pfam | PF00628; PF02182; PF12148; PF00240 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.033713(Chimpanzee);0.019071(Mouse);0.002166(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WY8 (NMR - ) 1Z6U (X-ray 2.10A ) 2E6S (NMR - ) 3OLN (X-ray 2.30A ) 4PW5 (X-ray 2.20A ) 4PW6 (X-ray 3.79A ) 4PW7 (X-ray 2.00A ) 4TVR (X-ray 2.29A ) 5YCO (X-ray 2.20A ) |
| DBSNP | rs147971931 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00358, ECO:0000269|PubMed:12176013, ECO:0000269|PubMed:23404503, ECO:0000269|PubMed:27129234, ECO:0000269|PubMed:27743347, ECO:0000269|PubMed:29923055, ECO:0000269|PubMed:30335751}. Chromosome {ECO:0000269|PubMed:27129234}. Note=Enriched at genomic loci that are enriched for 5-hydroxymethylcytosine (5hmC). {ECO:0000269|PubMed:27129234}. |
| Mouse PG classification | NA |
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