| Gene Information | |
|---|---|
| Gene Name | NIPK |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (SINK) (p65-interacting inhibitor of NF-kappa-B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96RU7 |
| Gene Card | TRIB3 |
| Uniprot ID | Q96RU7 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest expression in liver, pancreas, peripheral blood leukocytes and bone marrow. Also highly expressed in a number of primary lung, colon and breast tumors. Expressed in spleen, thymus, and prostate and is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, and kidney. {ECO:0000269|PubMed:12736262, ECO:0000269|PubMed:12743605, ECO:0000269|PubMed:15299019}. |
| Pharmacological Animal Models | 0.025380(Chimpanzee);0.001000(Mouse);0.002101(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs757496714 rs2295490 rs35051116 rs56291463 rs56342286 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22977230}. |
| Mouse PG classification | NA |
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