| Gene Information | |
|---|---|
| Gene Name | NUDCD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 583 |
| Protein Names | NudC domain-containing protein 1 (Chronic myelogenous leukemia tumor antigen 66) (Tumor antigen CML66) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000120526 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96RS6 |
| Gene Card | NUDCD1 |
| Uniprot ID | Q96RS6 |
| Pfam | PF04969 |
| In ASD | no |
| Allosteric Prediction | no (-0.849326038) |
| Ortholog in Animals | Alpaca_ NUDCD1 ( ortholog_one2one ) Dog_ NUDCD1 ( ortholog_one2one ) GuineaPig_ NUDCD1 ( ortholog_one2one ) Macaque_ NUDCD1 ( ortholog_one2one ) Mouse_ Nudcd1 ( ortholog_one2one ) Pig_ NUDCD1 ( ortholog_one2one ) Rat_ Nudcd1 ( ortholog_one2one ) Rabbit_ NUDCD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is specifically expressed in leukemias and a variety of solid tumor cell lines and is also detected in testis and heart. Isoform 2 is predominantly expressed in testis and weakly expressed in tumor cells. {ECO:0000269|PubMed:11416219, ECO:0000269|PubMed:14688378}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2980619 rs2980618 rs34660136 rs11550169 |
| Subcellular location [CC] | [Isoform 1]: Cytoplasm. Nucleus.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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