| Gene Information | |
|---|---|
| Gene Name | MINAR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 916 |
| Protein Names | Major intrinsically disordered Notch2-binding receptor 1 (Membrane integral NOTCH2-associated receptor 1) (Ubiquitination and mTOR signaling protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000169330 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UPX6 |
| Gene Card | MINAR1 |
| Uniprot ID | Q9UPX6 |
| Pfam | PF06789 |
| In ASD | no |
| Allosteric Prediction | no (-1.762823682) |
| Ortholog in Animals | Alpaca_ MINAR1 ( ortholog_one2one ) Dog_ MINAR1 ( ortholog_one2one ) GuineaPig_ MINAR1 ( ortholog_one2one ) Macaque_ MINAR1 ( ortholog_one2one ) Mouse_ Minar1 ( ortholog_one2one ) Pig_ MINAR1 ( ortholog_one2one ) Rat_ Minar1 ( ortholog_one2one ) Rabbit_ MINAR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MINAR2 |
| Tissue | adrenal.gland |
| Tissue Specificity | Widely expressed, including in breast epithelial cells and endothelial cells (at protein level). Expression is down-regulated in advanced breast tumors (at protein level). {ECO:0000269|PubMed:29329397}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11634652 rs2297773 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:29329397, ECO:0000269|PubMed:30080879}; Single-pass type IV membrane protein {ECO:0000269|PubMed:30080879}. |
| Mouse PG classification | NA |
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