| Gene Information | |
|---|---|
| Gene Name | NIK |
| Organism | Homo sapiens (Human) |
| Gene Length | 947 |
| Protein Names | Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q99558 |
| Gene Card | MAP3K14 |
| Uniprot ID | Q99558 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon. {ECO:0000269|PubMed:9020361}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002043(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4DN5 (X-ray 2.50A ) 4G3D (X-ray 2.90A ) 4IDT (X-ray 2.40A ) 4IDV (X-ray 2.90A ) 6WPP (X-ray 2.55A ) 6Z1Q (X-ray 2.42A ) 6Z1T (X-ray 2.31A ) |
| DBSNP | rs11574819 rs11574820 rs11867907 rs56302559 rs56036201 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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