| Gene Information | |
|---|---|
| Gene Name | SLURP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 97 |
| Protein Names | Secreted Ly-6/uPAR domain-containing protein 2 (Secreted LY6/PLAUR domain-containing protein 2) (Secreted Ly-6/uPAR-related protein 2) (SLURP-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000283992 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P0DP57 |
| Gene Card | SLURP2 |
| Uniprot ID | P0DP57 |
| Pfam | PF00021 |
| In ASD | no |
| Allosteric Prediction | no (-1.537390577) |
| Ortholog in Animals | Alpaca_ SLURP2 ( ortholog_one2one ) GuineaPig_ SLURP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at highest levels in cervix and esophagus, followed by adult and fetal skin. Expressed at lower levels in brain, lung, stomach, small intestine, colon, rectum, uterus, and thymus. Not detected in spleen nor bone marrow. Up-regulated 3-fold in psoriatic lesional skin (PubMed:12573258). In the epidermis, predominantly produced by keratinocytes of the suprabasal epidermal compartment (at protein level) (PubMed:16575903). In attached gingiva, produced at highest levels by basal cells located in the lowermost epithelial layers (at protein level) (PubMed:16575903). Detected in serum (at protein level) (PubMed:16575903). {ECO:0000269|PubMed:12573258, ECO:0000269|PubMed:16575903}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2N99 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:16575903}. |
| Mouse PG classification | NA |
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