Gene Information
Gene NameNIAM
OrganismHomo sapiens (Human)
Gene Length411
Protein NamesTransforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ3YBR2
Gene CardTBRG1
Uniprot IDQ3YBR2
PfamPF05965; PF05964
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell lymphoma. {ECO:0000269|PubMed:17110379}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2WZO  (X-ray  1.60A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:17110379}.
Mouse PG classificationNA
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