| Gene Information | |
|---|---|
| Gene Name | NHP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 153 |
| Protein Names | H/ACA ribonucleoprotein complex subunit 2 (Nucleolar protein family A member 2) (snoRNP protein NHP2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000145912 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9NX24 |
| Gene Card | NHP2 |
| Uniprot ID | Q9NX24 |
| Pfam | PF01248 |
| In ASD | no |
| Allosteric Prediction | no (-1.366004293) |
| Ortholog in Animals | Alpaca_ NHP2 ( ortholog_one2one ) Dog_ NHP2 ( ortholog_one2one ) GuineaPig_ NHP2 ( ortholog_one2one ) Macaque_ NHP2 ( ortholog_one2one ) Mouse_ Nhp2 ( ortholog_one2one ) Rat_ Nhp2 ( ortholog_one2one ) Rabbit_ NHP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RSL1D1, RPL7A, RPL10A |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus. Also expressed at lower levels in the liver. {ECO:0000269|PubMed:12020816}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);0.061538(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7BGB (EM 3.39A ) 7TRC (EM 3.30A ) 7V9A (EM 3.94A ) |
| DBSNP | rs139588879 rs121908090 rs121908089 |
| Subcellular location [CC] | Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies). |
| Mouse PG classification | NA |
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