Gene Information
Gene NameNGL1
OrganismHomo sapiens (Human)
Gene Length640
Protein NamesLeucine-rich repeat-containing protein 4C (Netrin-G1 ligand) (NGL-1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9HCJ2
Gene CardLRRC4C
Uniprot IDQ9HCJ2
PfamPF07679; PF13306; PF13855
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show very weak or no expression. {ECO:0000269|PubMed:14595443}.
Pharmacological Animal Models0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3ZYJ  (X-ray  3.25A 
DBSNP NA 
Subcellular location [CC]Postsynaptic cell membrane {ECO:0000269|PubMed:14595443, ECO:0000269|PubMed:21946559};
Single-pass type I membrane protein {ECO:0000269|PubMed:14595443, ECO:0000269|PubMed:21946559}.
Mouse PG classificationNA
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