| Gene Information | |
|---|---|
| Gene Name | NFKBIE |
| Organism | Homo sapiens (Human) |
| Gene Length | 500 |
| Protein Names | NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000146232 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O00221 |
| Gene Card | NFKBIE |
| Uniprot ID | O00221 |
| Pfam | PF12796 |
| In ASD | no |
| Allosteric Prediction | yes (0.173352659) |
| Ortholog in Animals | Alpaca_ NFKBIE ( ortholog_one2one ) Dog_ NFKBIE ( ortholog_one2one ) GuineaPig_ NFKBIE ( ortholog_one2one ) Macaque_ NFKBIE ( ortholog_one2one ) Mouse_ Nfkbie ( ortholog_one2one ) Pig_ NFKBIE ( ortholog_one2one ) Rat_ Nfkbie ( ortholog_one2one ) Rabbit_ NFKBIE ( ortholog_one2one ) |
| Ohnologs | BCL3, NFKBIA, NFKB1 |
| Paralogs | BCL3, POTEH, POTEB2, POTED, POTEG, POTEB3, POTEM, POTEJ, POTEF, POTEB, POTEE, POTEI, POTEC, POTEA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28362857 rs2233434 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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