| Gene Information | |
|---|---|
| Gene Name | NARS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 548 |
| Protein Names | Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) (Asparaginyl-tRNA synthetase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000134440 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O43776 |
| Gene Card | NARS1 |
| Uniprot ID | O43776 |
| Pfam | PF00152; PF01336 |
| In ASD | no |
| Allosteric Prediction | yes (0.095382193) |
| Ortholog in Animals | Alpaca_ NARS1 ( ortholog_one2one ) Dog_ NARS1 ( ortholog_one2one ) Macaque_ NARS1 ( ortholog_one2one ) Mouse_ Nars ( ortholog_one2one ) Pig_ NARS1 ( ortholog_one2one ) Rat_ Nars1 ( ortholog_one2one ) Rabbit_ NARS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DARS2, KARS1, DARS1, NARS2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4ZYA (X-ray 1.65A ) 5XIX (X-ray 2.25A ) |
| DBSNP | rs771435243 rs148893823 rs1402942713 rs138016359 rs769070609 rs770931044 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305|PubMed:9421509}. |
| Mouse PG classification | NA |
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