| Gene Information | |
|---|---|
| Gene Name | NET1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 797 |
| Protein Names | Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000173848 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y345 |
| Gene Card | SLC6A5 |
| Uniprot ID | Q9Y345 |
| Pfam | PF00209 |
| In ASD | yes |
| Allosteric Prediction | yes (0.04695389) |
| Ortholog in Animals | Alpaca_ NET1 ( ortholog_one2one ) Dog_ NET1 ( ortholog_one2one ) GuineaPig_ NET1 ( ortholog_one2one ) Macaque_ NET1 ( ortholog_one2one ) Mouse_ Net1 ( ortholog_one2one ) Pig_ NET1 ( ortholog_one2one ) Rat_ Net1 ( ortholog_one2one ) Rabbit_ NET1 ( ortholog_one2one ) |
| Ohnologs | ARHGEF3 |
| Paralogs | ARHGEF28, ARHGEF12, ARHGEF18, ARHGEF11, PLEKHG6, ARHGEF3, ARHGEF1, ARHGEF2 |
| Tissue | NA |
| Tissue Specificity | Expressed in medulla, and to a lesser extent in spinal cord and cerebellum. {ECO:0000269|PubMed:9845349}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs61736602 rs1443547 rs1443548 rs34243519 rs1443549 rs121908496 rs121908498 rs745539706 rs3740870 rs1805091 rs121908494 rs7944684 rs121908497 rs281864926 rs16906628 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16751771, ECO:0000269|PubMed:31370103}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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