| Gene Information | |
|---|---|
| Gene Name | NET1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 596 |
| Protein Names | Neuroepithelial cell-transforming gene 1 protein (Proto-oncogene p65 Net1) (Rho guanine nucleotide exchange factor 8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000173848 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q7Z628 |
| Gene Card | NET1 |
| Uniprot ID | Q7Z628 |
| Pfam | PF00169; PF00621 |
| In ASD | no |
| Allosteric Prediction | yes (0.04695389) |
| Ortholog in Animals | Alpaca_ NET1 ( ortholog_one2one ) Dog_ NET1 ( ortholog_one2one ) GuineaPig_ NET1 ( ortholog_one2one ) Macaque_ NET1 ( ortholog_one2one ) Mouse_ Net1 ( ortholog_one2one ) Pig_ NET1 ( ortholog_one2one ) Rat_ Net1 ( ortholog_one2one ) Rabbit_ NET1 ( ortholog_one2one ) |
| Ohnologs | ARHGEF3 |
| Paralogs | ARHGEF28, ARHGEF12, ARHGEF18, ARHGEF11, PLEKHG6, ARHGEF3, ARHGEF1, ARHGEF2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:8649828}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3EO2 (X-ray 2.60A ) 4XH9 (X-ray 2.00A ) |
| DBSNP | rs34658946 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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