| Gene Information | |
|---|---|
| Gene Name | NEMF |
| Organism | Homo sapiens (Human) |
| Gene Length | 1076 |
| Protein Names | Ribosome quality control complex subunit NEMF (Antigen NY-CO-1) (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000165525 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O60524 |
| Gene Card | NEMF |
| Uniprot ID | O60524 |
| Pfam | PF11923; PF05670 |
| In ASD | no |
| Allosteric Prediction | no (-1.167921769) |
| Ortholog in Animals | Alpaca_ NEMF ( ortholog_one2one ) Dog_ NEMF ( ortholog_one2one ) GuineaPig_ NEMF ( ortholog_one2one ) Macaque_ NEMF ( ortholog_one2one ) Mouse_ Nemf ( ortholog_one2one ) Pig_ NEMF ( ortholog_one2one ) Rabbit_ NEMF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis. {ECO:0000269|PubMed:16103875, ECO:0000269|PubMed:33048237}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3J92 (EM 3.60A ) |
| DBSNP | rs3100906 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:25578875}. Nucleus {ECO:0000305|PubMed:16103875}. |
| Mouse PG classification | NA |
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