| Gene Information | |
|---|---|
| Gene Name | NELFB |
| Organism | Homo sapiens (Human) |
| Gene Length | 580 |
| Protein Names | Negative elongation factor B (NELF-B) (Cofactor of BRCA1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000188986 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WX92 |
| Gene Card | NELFB |
| Uniprot ID | Q8WX92 |
| Pfam | PF06209 |
| In ASD | no |
| Allosteric Prediction | no (-0.312867604) |
| Ortholog in Animals | Alpaca_ NELFB ( ortholog_one2one ) Dog_ NELFB ( ortholog_one2one ) GuineaPig_ NELFB ( ortholog_one2one ) Macaque_ NELFB ( ortholog_one2one ) Mouse_ Nelfb ( ortholog_one2one ) Pig_ NELFB ( ortholog_one2one ) Rat_ Nelfb ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12612062}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.076473(Mouse);0.142419(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6GML (EM 3.20A ) 7PKS (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11739404}. |
| Mouse PG classification | NA |
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