| Gene Information | |
|---|---|
| Gene Name | SEPTIN3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | Neuronal-specific septin-3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000100167 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9UH03 |
| Gene Card | SEPTIN3 |
| Uniprot ID | Q9UH03 |
| Pfam | PF00735 |
| In ASD | no |
| Allosteric Prediction | no (-0.569684673) |
| Ortholog in Animals | Alpaca_ SEPTIN3 ( ortholog_one2one ) Dog_ SEPTIN3 ( ortholog_one2one ) Macaque_ SEPTIN3 ( ortholog_one2one ) Mouse_ Septin3 ( ortholog_one2one ) Pig_ SEPTIN3 ( ortholog_one2one ) Rat_ Septin3 ( ortholog_one2one ) |
| Ohnologs | SEPTIN12, SEPTIN9 |
| Paralogs | SEPTIN11, SEPTIN8, SEPTIN12, SEPTIN10, SEPTIN1, SEPTIN9, TMEM250, SEPTIN7, SEPTIN6, SEPTIN5, SEPTIN2, SEPTIN14 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Brain-specific. {ECO:0000269|PubMed:11322766, ECO:0000269|PubMed:15915442}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.124048(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3SOP (X-ray 2.88A ) 4Z51 (X-ray 1.86A ) 4Z54 (X-ray 1.83A ) 6UQQ (X-ray 2.75A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Synapse {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |