| Gene Information | |
|---|---|
| Gene Name | NECAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 275 |
| Protein Names | Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000089818 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NC96 |
| Gene Card | NECAP1 |
| Uniprot ID | Q8NC96 |
| Pfam | PF07933 |
| In ASD | no |
| Allosteric Prediction | no (-0.324958344) |
| Ortholog in Animals | Alpaca_ NECAP1 ( ortholog_one2one ) Dog_ NECAP1 ( ortholog_one2one ) GuineaPig_ NECAP1 ( ortholog_one2one ) Macaque_ NECAP1 ( ortholog_one2one ) Mouse_ Necap1 ( ortholog_one2one ) Pig_ NECAP1 ( ortholog_one2one ) Rat_ Necap1 ( ortholog_one2one ) Rabbit_ NECAP1 ( ortholog_one2one ) |
| Ohnologs | NECAP2 |
| Paralogs | NECAP2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.018182(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6RH5 (NMR - ) 6RH6 (NMR - ) |
| DBSNP | rs2231752 |
| Subcellular location [CC] | Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Colocalizes with AP-2 at the plasma membrane. {ECO:0000250}. |
| Mouse PG classification | NA |
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