| Gene Information | |
|---|---|
| Gene Name | NECAB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 396 |
| Protein Names | N-terminal EF-hand calcium-binding protein 3 (Amyloid-beta A4 protein-binding family A member 2-binding protein) (Nek2-interacting protein 1) (Neuronal calcium-binding protein 3) (X11L-binding protein 51) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000125967 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96P71 |
| Gene Card | NECAB3 |
| Uniprot ID | Q96P71 |
| Pfam | PF03992; PF13202 |
| In ASD | no |
| Allosteric Prediction | no (-1.023316893) |
| Ortholog in Animals | Alpaca_ NECAB3 ( ortholog_one2many ) Dog_ NECAB3 ( ortholog_one2one ) GuineaPig_ NECAB3 ( ortholog_one2one ) Macaque_ NECAB3 ( ortholog_one2one ) Mouse_ Necab3 ( ortholog_one2one ) Pig_ NECAB3 ( ortholog_one2one ) Rabbit_ NECAB3 ( ortholog_one2one ) |
| Ohnologs | NECAB2, NECAB1 |
| Paralogs | NECAB1, NECAB2 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas. {ECO:0000269|PubMed:10833507, ECO:0000269|PubMed:12044471}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.420300(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17124890 |
| Subcellular location [CC] | Golgi apparatus {ECO:0000269|PubMed:10833507, ECO:0000269|PubMed:14697346, ECO:0000269|PubMed:26948053}. |
| Mouse PG classification | NA |
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