Gene Information
Gene NameNEC2
OrganismHomo sapiens (Human)
Gene Length638
Protein NamesNeuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP16519
Gene CardPCSK2
Uniprot IDP16519
PfamPF01483; PF00082; PF16470
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.000730(Chimpanzee);0.001000(Mouse);0.005990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs201718679  rs17854040  rs144151196  rs780820865  rs200711626  rs17857236  rs139619496 
Subcellular location [CC]Cytoplasmic vesicle, secretory vesicle. Secreted {ECO:0000269|PubMed:28719828}. Note=Localized in the secretion granules.
Mouse PG classificationNA
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