Gene Information
Gene NameVPS28
OrganismHomo sapiens (Human)
Gene Length221
Protein NamesVacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000160948 )
3 ( ENSG00000285339 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UK41
Gene CardVPS28
Uniprot IDQ9UK41
PfamPF03997
In ASDno
Allosteric Predictionyes (0.019245675)
Ortholog in AnimalsAlpaca_ VPS28 ( ortholog_one2many )
Dog_ VPS28 ( ortholog_one2one )
GuineaPig_ VPS28 ( ortholog_one2one )
Macaque_ VPS28 ( ortholog_one2one )
Mouse_ Vps28 ( ortholog_one2one )
Pig_ VPS28 ( ortholog_one2one )
Rat_ Vps28 ( ortholog_one2one )
Rabbit_ VPS28 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.760609(Rat);0.268182(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6VME  (X-ray  2.19A 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:11916981}. Late endosome membrane {ECO:0000269|PubMed:11916981};
Peripheral membrane protein {ECO:0000269|PubMed:11916981}.
Mouse PG classificationNA
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