| Gene Information | |
|---|---|
| Gene Name | NDUFS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 264 |
| Protein Names | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 7.1.1.2) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit) |
| Target Name | nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000213619 ) 3 ( ENSG00000285387 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O75489 |
| Gene Card | NDUFS3 |
| Uniprot ID | O75489 |
| Pfam | PF00329 |
| In ASD | no |
| Allosteric Prediction | no (-0.038499801) |
| Ortholog in Animals | Alpaca_ NDUFS3 ( ortholog_one2one ) GuineaPig_ NDUFS3 ( ortholog_one2one ) Macaque_ NDUFS3 ( ortholog_one2one ) Mouse_ Ndufs3 ( ortholog_one2one ) Pig_ NDUFS3 ( ortholog_one2one ) Rat_ Ndufs3 ( ortholog_one2one ) Rabbit_ NDUFS3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.642594(Rat);0.245722(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTB (EM 3.40A ) 5XTD (EM 3.70A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs142248674 rs28939714 rs104894270 rs9600 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:18826940, ECO:0000305|PubMed:12611891, ECO:0000305|PubMed:17209039}; Peripheral membrane protein {ECO:0000305|PubMed:18826940}; Matrix side {ECO:0000269|PubMed:18826940}. |
| Mouse PG classification | NA |
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