| Gene Information | |
|---|---|
| Gene Name | NDUFS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 463 |
| Protein Names | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit) |
| Target Name | nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000158864 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O75306 |
| Gene Card | NDUFS2 |
| Uniprot ID | O75306 |
| Pfam | PF00346 |
| In ASD | no |
| Allosteric Prediction | yes (0.014202323) |
| Ortholog in Animals | Alpaca_ NDUFS2 ( ortholog_one2one ) Dog_ NDUFS2 ( ortholog_one2one ) GuineaPig_ NDUFS2 ( ortholog_one2one ) Mouse_ Ndufs2 ( ortholog_one2one ) Pig_ NDUFS2 ( ortholog_one2one ) Rat_ Ndufs2 ( ortholog_one2one ) Rabbit_ NDUFS2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.641955(Rat);0.255652(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 5XTB (EM 3.40A ) 5XTC (EM 3.70A ) 5XTD (EM 3.70A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs11538340 rs121434427 rs16827493 rs121434428 rs11576415 rs121434429 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000305|PubMed:12611891, ECO:0000305|PubMed:9585441}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q641Y2}; Matrix side {ECO:0000250|UniProtKB:Q641Y2}. |
| Mouse PG classification | NA |
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