| Gene Information | |
|---|---|
| Gene Name | NDUFS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 727 |
| Protein Names | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD) |
| Target Name | nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000023228 ) 3 ( ENSG00000283447 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P28331 |
| Gene Card | NDUFS1 |
| Uniprot ID | P28331 |
| Pfam | PF00384; PF10588; PF09326 |
| In ASD | no |
| Allosteric Prediction | no (-0.008192372) |
| Ortholog in Animals | Alpaca_ NDUFS1 ( ortholog_one2one ) Dog_ NDUFS1 ( ortholog_one2one ) GuineaPig_ NDUFS1 ( ortholog_one2one ) Macaque_ NDUFS1 ( ortholog_one2one ) Mouse_ Ndufs1 ( ortholog_one2one ) Pig_ NDUFS1 ( ortholog_one2one ) Rat_ Ndufs1 ( ortholog_one2one ) Rabbit_ NDUFS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CIAO3, NARF |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTB (EM 3.40A ) 5XTD (EM 3.70A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs17856901 rs199422225 rs199422224 rs786205666 rs1044049 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000305|PubMed:12611891, ECO:0000305|PubMed:30879903}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15690}; Matrix side {ECO:0000250|UniProtKB:P15690}. |
| Mouse PG classification | NA |
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