| Gene Information | |
|---|---|
| Gene Name | NDUFAF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 333 |
| Protein Names | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 (Putative phytoene synthase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000156170 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q330K2 |
| Gene Card | NDUFAF6 |
| Uniprot ID | Q330K2 |
| Pfam | PF00494 |
| In ASD | no |
| Allosteric Prediction | no (-1.054063301) |
| Ortholog in Animals | Alpaca_ NDUFAF6 ( ortholog_one2one ) Dog_ NDUFAF6 ( ortholog_one2one ) GuineaPig_ NDUFAF6 ( ortholog_one2one ) Macaque_ NDUFAF6 ( ortholog_one2one ) Mouse_ Ndufaf6 ( ortholog_one2one ) Pig_ NDUFAF6 ( ortholog_one2one ) Rat_ Ndufaf6 ( ortholog_one2one ) Rabbit_ NDUFAF6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MMGT1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. A lower expression is observed in lung and kidney compared to heart, muscle and liver (PubMed:27466185). In the kidney, expression is high in the basal zone of the proximal tubular cells (PubMed:27466185). {ECO:0000269|PubMed:27466185}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1057519085 rs1057519084 rs137853184 rs201732170 rs201088736 rs768273248 rs1057519086 |
| Subcellular location [CC] | [Isoform 1]: Mitochondrion inner membrane. Note=Peripherally localized on the matrix face of the mitochondrial inner membrane.; [Isoform 2]: Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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