Gene Information
Gene NameUPK3B
OrganismHomo sapiens (Human)
Gene Length320
Protein NamesUroplakin-3b (UP3b) (Uroplakin IIIb) (UPIIIb) (p35)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000243566 )
3 ( ENSG00000276184 )
Evolutionary StageMammalia
AlphaFoldDBQ9BT76
Gene CardUPK3B
Uniprot IDQ9BT76
PfamNA
In ASDno
Allosteric Predictionno (-1.64974992)
Ortholog in AnimalsGuineaPig_ UPK3B ( ortholog_one2one )
Macaque_ UPK3B ( ortholog_one2one )
Mouse_ Upk3b ( ortholog_one2one )
Pig_ UPK3B ( ortholog_one2one )
Rat_ Upk3b ( ortholog_one2one )
Rabbit_ UPK3B ( ortholog_one2one )
OhnologsNA
ParalogsUPK3BL2, UPK3BL1, UPK3A
Tissuelung, esophagus.mucosa, greater.omentum
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1636632  rs1799126 
Subcellular location [CC]Cell membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). {ECO:0000269|PubMed:12446744}.
Mouse PG classificationNA
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