| Gene Information | |
|---|---|
| Gene Name | NDUFA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 81 |
| Protein Names | Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit) |
| Target Name | nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000189043 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O00483 |
| Gene Card | NDUFA4 |
| Uniprot ID | O00483 |
| Pfam | PF06522 |
| In ASD | no |
| Allosteric Prediction | no (-0.819689574) |
| Ortholog in Animals | Alpaca_ NDUFA4 ( ortholog_one2one ) GuineaPig_ NDUFA4 ( ortholog_one2one ) Macaque_ NDUFA4 ( ortholog_one2one ) Mouse_ Ndufa4 ( ortholog_one2one ) Pig_ NDUFA4 ( ortholog_one2one ) Rat_ Ndufa4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NDUFA4L2, C15orf48 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.029817(Mouse);NULL(Rat);0.231991(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5Z62 (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:23746447, ECO:0000269|PubMed:30030519}; Single-pass membrane protein {ECO:0000269|PubMed:30030519}. |
| Mouse PG classification | NA |
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