| Gene Information | |
|---|---|
| Gene Name | NDST4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 872 |
| Protein Names | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST-4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 4 (EC 2.8.2.-)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000138653 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9H3R1 |
| Gene Card | NDST4 |
| Uniprot ID | Q9H3R1 |
| Pfam | PF12062; PF00685 |
| In ASD | no |
| Allosteric Prediction | no (-0.860286055) |
| Ortholog in Animals | Alpaca_ NDST4 ( ortholog_one2one ) Dog_ NDST4 ( ortholog_one2one ) GuineaPig_ NDST4 ( ortholog_one2one ) Macaque_ NDST4 ( ortholog_one2one ) Mouse_ Ndst4 ( ortholog_one2one ) Pig_ NDST4 ( ortholog_one2one ) Rat_ Ndst4 ( ortholog_one2one ) Rabbit_ NDST4 ( ortholog_one2one ) |
| Ohnologs | NDST1, NDST2 |
| Paralogs | HS3ST3A1, NDST1, HS3ST1, HS3ST4, HS3ST2, NDST3, HS3ST6, NDST2, HS3ST3B1, HS3ST5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35181627 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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