Gene Information
Gene NameVPS54
OrganismHomo sapiens (Human)
Gene Length977
Protein NamesVacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000143952 )
Evolutionary StageEukaryota
AlphaFoldDBQ9P1Q0
Gene CardVPS54
Uniprot IDQ9P1Q0
PfamPF07928; PF10475
In ASDno
Allosteric Predictionno (-1.257329001)
Ortholog in AnimalsAlpaca_ VPS54 ( ortholog_one2one )
Dog_ VPS54 ( ortholog_one2one )
GuineaPig_ VPS54 ( ortholog_one2one )
Macaque_ VPS54 ( ortholog_one2one )
Mouse_ Vps54 ( ortholog_one2one )
Pig_ VPS54 ( ortholog_one2one )
Rat_ Vps54 ( ortholog_one2one )
Rabbit_ VPS54 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.104525(Rat);0.082030(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34015596  rs11558741 
Subcellular location [CC]Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:18367545, ECO:0000269|PubMed:25799061}. Membrane {ECO:0000250|UniProtKB:Q9JMK8}. Note=Associates with membranes in an EIPR1-independent manner. {ECO:0000250|UniProtKB:Q9JMK8}.
Mouse PG classificationNA
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