| Gene Information | |
|---|---|
| Gene Name | NDST3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 873 |
| Protein Names | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST-3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase NDST3 (EC 3.-.-.-); [heparan sulfate]-glucosamine N-sulfotransferase NDST3 (EC 2.8.2.8)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000164100 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O95803 |
| Gene Card | NDST3 |
| Uniprot ID | O95803 |
| Pfam | PF12062; PF00685 |
| In ASD | no |
| Allosteric Prediction | no (-1.105229167) |
| Ortholog in Animals | Alpaca_ NDST3 ( ortholog_one2one ) Dog_ NDST3 ( ortholog_one2one ) GuineaPig_ NDST3 ( ortholog_one2one ) Macaque_ NDST3 ( ortholog_one2one ) Mouse_ Ndst3 ( ortholog_one2one ) Pig_ NDST3 ( ortholog_one2one ) Rat_ Ndst3 ( ortholog_one2one ) Rabbit_ NDST3 ( ortholog_one2one ) |
| Ohnologs | NDST1, NDST2 |
| Paralogs | HS3ST3A1, NDST1, HS3ST1, HS3ST4, HS3ST2, HS3ST6, NDST4, NDST2, HS3ST3B1, HS3ST5 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and fetal thymus. Not detected in adult/ fetal heart and skeletal muscle. {ECO:0000269|PubMed:9915799}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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