| Gene Information | |
|---|---|
| Gene Name | NDFIP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 336 |
| Protein Names | NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000102471 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NV92 |
| Gene Card | NDFIP2 |
| Uniprot ID | Q9NV92 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.528168695) |
| Ortholog in Animals | Alpaca_ NDFIP2 ( ortholog_one2one ) Dog_ NDFIP2 ( ortholog_one2one ) GuineaPig_ NDFIP2 ( ortholog_one2one ) Macaque_ NDFIP2 ( ortholog_one2one ) Mouse_ Ndfip2 ( ortholog_one2one ) Pig_ NDFIP2 ( ortholog_one2one ) Rat_ Ndfip2 ( ortholog_one2one ) Rabbit_ NDFIP2 ( ortholog_one2one ) |
| Ohnologs | NDFIP1 |
| Paralogs | NDFIP1 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta. {ECO:0000269|PubMed:12796489}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs55887763 rs11549502 |
| Subcellular location [CC] | Endosome membrane {ECO:0000269|PubMed:18776082}; Multi-pass membrane protein {ECO:0000269|PubMed:18776082}. Golgi apparatus membrane {ECO:0000269|PubMed:12796489, ECO:0000269|PubMed:26363003}. Endosome, multivesicular body membrane {ECO:0000269|PubMed:26363003}. |
| Mouse PG classification | NA |
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