| Gene Information | |
|---|---|
| Gene Name | NDEL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 345 |
| Protein Names | Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000166579 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9GZM8 |
| Gene Card | NDEL1 |
| Uniprot ID | Q9GZM8 |
| Pfam | PF04880 |
| In ASD | no |
| Allosteric Prediction | no (-0.706550218) |
| Ortholog in Animals | Alpaca_ NDEL1 ( ortholog_one2one ) Alpaca_ NDEL1 ( ortholog_one2many ) Dog_ NDEL1 ( ortholog_one2one ) GuineaPig_ NDEL1 ( ortholog_one2one ) Macaque_ NDEL1 ( ortholog_one2one ) Mouse_ Ndel1 ( ortholog_one2one ) Pig_ NDEL1 ( ortholog_one2one ) Rat_ Ndel1 ( ortholog_one2one ) Rabbit_ NDEL1 ( ortholog_one2one ) |
| Ohnologs | NDE1 |
| Paralogs | NDE1 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. {ECO:0000269|PubMed:16005531}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2V66 (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the cell body of the motor neurons and colocalizes with assembled neurofilaments within axonal processes. Localizes to the microtubules of the manchette in elongated spermatids. Colocalizes with DISC1 in the perinuclear region, including the centrosome (By similarity). Localizes to the interphase centrosome and the mitotic spindle. Localizes to the kinetochore in a CENPF-dependent manner. {ECO:0000250}. |
| Mouse PG classification | NA |
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