| Gene Information | |
|---|---|
| Gene Name | NDE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 335 |
| Protein Names | Nuclear distribution protein nudE homolog 1 (NudE) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000072864 ) 3 ( ENSG00000275911 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NXR1 |
| Gene Card | NDE1 |
| Uniprot ID | Q9NXR1 |
| Pfam | PF04880 |
| In ASD | no |
| Allosteric Prediction | no (-0.283791344) |
| Ortholog in Animals | Alpaca_ NDE1 ( ortholog_one2one ) Dog_ NDE1 ( ortholog_one2one ) GuineaPig_ NDE1 ( ortholog_one2one ) Macaque_ NDE1 ( ortholog_one2one ) Mouse_ Nde1 ( ortholog_one2one ) Pig_ NDE1 ( ortholog_one2one ) Rat_ Nde1 ( ortholog_one2one ) Rabbit_ NDE1 ( ortholog_one2one ) |
| Ohnologs | NDEL1 |
| Paralogs | NDEL1 |
| Tissue | NA |
| Tissue Specificity | Expressed in the neuroepithelium throughout the developing brain, including the cerebral cortex and cerebellum. {ECO:0000269|PubMed:21529752}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7E1T (X-ray 2.45A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Note=Localizes to the interphase and S phase centrosome. During mitosis, partially associated with the mitotic spindle. Concentrates at the plus ends of microtubules coincident with kinetochores in metaphase and anaphase in a CENPF-dependent manner. Also localizes to the cleavage furrow during cytokinesis. manner. Also localizes to the cleavage furrow during cytokinesis. |
| Mouse PG classification | HPG |
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