| Gene Information | |
|---|---|
| Gene Name | NCR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 276 |
| Protein Names | Natural cytotoxicity triggering receptor 2 (Lymphocyte antigen 95 homolog) (NK cell-activating receptor) (Natural killer cell p44-related protein) (NK-p44) (NKp44) (CD antigen CD336) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000096264 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O95944 |
| Gene Card | NCR2 |
| Uniprot ID | O95944 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.093441968) |
| Ortholog in Animals | Alpaca_ NCR2 ( ortholog_one2many ) Macaque_ NCR2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TREML4, TREML2 |
| Tissue | NA |
| Tissue Specificity | Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells. {ECO:0000269|PubMed:10049942}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1HKF (X-ray 2.20A ) |
| DBSNP | rs9471577 rs2236369 rs2273961 rs2273962 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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