Gene Information
Gene NameNCOR2
OrganismHomo sapiens (Human)
Gene Length2514
Protein NamesNuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000196498 )
Evolutionary StageEukaryota
AlphaFoldDBQ9Y618
Gene CardNCOR2
Uniprot IDQ9Y618
PfamPF15784; PF00249
In ASDno
Allosteric Predictionyes (0.536026803)
Ortholog in AnimalsAlpaca_ NCOR2 ( ortholog_one2one )
Dog_ NCOR2 ( ortholog_one2one )
GuineaPig_ NCOR2 ( ortholog_one2one )
Macaque_ NCOR2 ( ortholog_one2one )
Mouse_ Ncor2 ( ortholog_one2one )
Pig_ NCOR2 ( ortholog_one2one )
Rat_ Ncor2 ( ortholog_one2one )
Rabbit_ NCOR2 ( ortholog_one2one )
OhnologsNCOR1
ParalogsNCOR1
TissueNA
Tissue SpecificityUbiquitous. High levels of expression are detected in lung, spleen and brain.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.032727(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1KKQ  (X-ray  3.00A  1R2B  (X-ray  2.20A  1XC5  (NMR  2GPV  (X-ray  2.85A  2L5G  (NMR  2LTP  (NMR  2ODD  (NMR  2RT5  (NMR  3R29  (X-ray  2.90A  3R2A  (X-ray  3.00A  4A69  (X-ray  2.06A  4OAR  (X-ray  2.41A  5X8Q  (X-ray  2.20A  5X8X  (X-ray  2.60A  5ZOO  (X-ray  1.85A  5ZOP  (X-ray  2.70A  6A22  (X-ray  2.55A  6IVX  (X-ray  2.35A  6PDZ  (X-ray  2.10A 
DBSNP rs7978237  rs2229840  rs2230944 
Subcellular location [CC]Nucleus.
Mouse PG classificationNA
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