| Gene Information | |
|---|---|
| Gene Name | NCOA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 614 |
| Protein Names | Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000266412 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q13772 |
| Gene Card | NCOA4 |
| Uniprot ID | Q13772 |
| Pfam | PF12489 |
| In ASD | no |
| Allosteric Prediction | no (-0.171159927) |
| Ortholog in Animals | Alpaca_ NCOA4 ( ortholog_one2one ) GuineaPig_ NCOA4 ( ortholog_one2one ) Macaque_ NCOA4 ( ortholog_one2one ) Mouse_ Ncoa4 ( ortholog_one2one ) Pig_ NCOA4 ( ortholog_one2one ) Rat_ Ncoa4 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1T5Z (X-ray 2.30A ) |
| DBSNP | rs782517064 rs1132111 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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